List of Peptides Used In Skin Care

Looking for the best peptides to include in your skincare routine? Check out our comprehensive list of the top peptides used in skincare, and learn how these powerful ingredients can help improve your skin’s texture, firmness, and overall appearance. Whether you’re looking to target fine lines and wrinkles, combat dryness and dullness with a peptide moizturizer, or just give your skin a healthy, youthful glow, we’ve got you covered. Discover the benefits of peptides for skincare today!

Acetylarginyltryptophyl Diphenylglycine

Acetylarginyltryptophyl diphenylglycine is a synthetic tetrapeptide designed to improve firmness and sagginess in mature skin. This skin-communicating peptide prevents the breakdown of proteins like collagen, leading to firmer, more youthful-looking skin.

Acetylarginyltryptophyl Diphenylglycine is made by reacting acetic acid with arginine, phenylglycine, and tryptophan. This peptide is sold under the name Relistase® when combined with glycerin. In in-vivo tests, applying 4% Relistase for 8 weeks on mature women resulted in a significant improvement in skin elasticity and tightness.

Acetyl Dipeptide-1 Cetyl Ester

Acetyl dipeptide-1 cetyl ester protects skin’s collagen-making cells from glycation and helps to prevent irritation. This synthetic peptide combines acetic acid, cetyl alcohol, and dipeptide-1. Research has shown that it It works by stimulating skin nerve cells to release an opioid messenger molecule, met-enkephalin, which provides a relaxing and pain-relieving effect.

Acetyl dipeptide-1 cetyl ester is considered safe and is used in cosmetics at low concentrations. It can also prevent wrinkles and expression lines due to its muscle relaxation properties. In comparison to 4-t-Butylcyclohexanol, another soothing molecule, both molecules work to relieve burning and stinging sensations, with 4-t-Butylcyclohexanol being slightly more effective.

Acetyl Hexapeptide-1

Acetyl hexapeptide-1, also known as Melitane, is a synthetic peptide that offers numerous benefits for the skin. It helps to protect the skin from environmental aggressors by calming it down, while also promoting a more even skin tone by regulating how melanin moves through the skin. This peptide stimulates melanin production by interacting with the MC1R receptor on skin cells, which helps to boost a natural or artificial tan and provides additional protection against UV-induced DNA damage and free radical damage. Acetyl hexapeptide-1 also reduces the number of sunburn cells, attesting to its DNA repair action, thereby maximizing its anti-aging benefits. Additionally, it limits the expression of biochemical inflammation mediators and offers significant protection against UV-induced erythema, reducing skin redness and promoting a healthy glow.

Overall, Acetyl hexapeptide-1 is a potent skincare ingredient that provides diverse benefits for the skin. It not only helps to defend the skin against environmental damage but also boosts melanin production, promotes an even skin tone, reduces inflammation, and provides protection against UV-induced erythema.

Acetyl Hexapeptide-8

Acetyl hexapeptide-8, also known as Argireline, is a synthetic peptide used in skin care products to help reduce the appearance of fine lines and wrinkles. It works by temporarily limiting the overproduction and release of neurotransmitters that initiate and control the intensity of facial muscle contractions, thus relaxing the muscles and reducing the appearance of wrinkles. Additionally, studies have shown that this peptide can support skin’s collagen and preserve a firmer appearance.

While the manufacturer claims that Argireline has a “Botox-like effect” by targeting the same wrinkle-forming mechanism as Botox, the extent to which it can prevent muscles from contracting is much lower than that of Botox. While Acetyl Hexapeptide-8 does have some ability to smooth wrinkles, it is not a collagen builder or preventer of structural aging.

Acetyl Hexapeptide-37

Acetyl hexapeptide-37, known by the trade name Diffuporine®, improves the hydration of skin by working with the water channels in the skin’s surface layers. This can alleviate dryness and dehydration, although there is limited independent research on its effectiveness. However, Lipotec, the supplier, has conducted research on this peptide and has provided third-party studies to support its use. Considering the wider field of research on peptides for skin, acetyl hexapeptide-37 is recommended, especially for those with dehydrated skin.

Acetyl hexapeptide-37 increases aquaporin 3 expression, which can improve the flow of water from the lower layer of the skin to the outermost layer. This peptide can enhance the skin’s moisture, stimulate protein synthesis, and promote cell growth, which can help rejuvenate the skin.

Acetyl Octapeptide-3

Acetyl Octapeptide-3, also known as SNAP-8, claims to improve the appearance of aging signs caused by repetitive facial expressions. Additionally, it has been suggested that Acetyl Octapeptide-3 can influence muscle contractions and lead to a more relaxed and line-free face, particularly around the forehead and eyes.

This is a synthetic peptide complex composed of aspartic acid, glutamic acid, glutamine, and methionine. The peptide has water-binding properties and can potentially help hydrate and smooth the skin, as well as theoretically restoring skin. It is also a cost-effective alternative to botulinum toxin, and is popular in anti-wrinkle cosmetics.

Acetyl sh-Hexapeptide-5 Amide Acetate

Acetyl sh-hexapeptide-5 amide acetate, also known as hexapeptide-5, is a synthetic peptide that has been designed to mimic a portion of the fibronectin molecule in the skin. It reinforces the skin’s surface by increasing its resilience, tautness, and smoothness, resulting in a firmer and lifted appearance. Additionally, it helps to hydrate the skin by binding water to its surface, similar to the effects of hyaluronic acid.

Acetyl sh-hexapeptide-5 amide acetate is a biomimetic peptide that is derived from versican and helps to reinforce the connective tissue in the dermis and the beauty columns (skin ligaments). It boosts the fibrillin-versican-hyaluronan elastic-hydrated matrix to increase firmness and viscoelasticity in the skin. As a result, the beauty columns are repositioned to their original position, providing a scalpel-free retouch.

Acetyl Tetrapeptide-5

Acetyl Tetrapeptide-5 is a synthetic peptide that has been claimed to provide multiple benefits to the skin when applied topically. It is believed to have calming, smoothing, hydrating, and firmness-enhancing effects, and is particularly effective in reducing under-eye puffiness caused by fluid accumulation, such as from allergies. It is also claimed to interrupt the process of glycation in the skin, which can cause the skin’s supportive elements to weaken, leading to wrinkles and loss of firmness.

It is important to note that there can be multiple reasons for under-eye puffiness, and fat accumulation is one of the major causes that cannot be easily addressed by topical treatments. However, if the puffiness is caused by water accumulation, using an eye cream with Acetyl Tetrapeptide-5 could be a viable option.

Acetyl Tetrapeptide-9

Acetyl tetrapeptide-9 has been found to have remarkable properties in visibly restoring the natural support of the skin, which includes a specialized protein called lumican. Lumican helps to maintain the smoothness and tautness of the skin, which are important characteristics of youthful-looking skin.

Acetyl tetrapeptide-9 is a synthetic peptide that is created through the chemical reaction of acetylation with tetrapeptide-9. The latter is composed of four amino acids, including aspartic acid, glutamine, histidine, and valine.

The benefits of acetyl tetrapeptide-9 have been observed in numerous studies. It has been found to enhance the synthesis of collagen, which is a key component of the skin’s structure, and improve the elasticity of the skin. It also helps to reduce the appearance of fine lines and wrinkles by promoting the production of hyaluronic acid, a substance that keeps the skin hydrated and plump. In addition, acetyl tetrapeptide-9 has antioxidant properties, which help to protect the skin from environmental stressors such as pollution and UV radiation. Its multifaceted benefits make acetyl tetrapeptide-9 a highly sought-after ingredient in anti-aging skincare products.

Acetyl Tetrapeptide-11

Acetyl tetrapeptide-11 is a synthetic peptide that interacts with a signaling protein found on the skin’s surface to promote healthier-looking and feeling skin. This peptide is created through the acetylation of tetrapeptide-11, a chain of four amino acids consisting of leucine, proline, and tyrosine.

Acetyl tetrapeptide-11 works at the cellular level, stimulating collagen synthesis and enhancing the interaction between the skin’s building blocks. It helps distribute collagen fibers correctly in the extracellular matrix, strengthening the bonding between the epidermis and dermis, and improving the junction between them. As a result, this peptide helps reduce wrinkles and increase skin density, leading to more youthful-looking skin.

Arginine/Lysine Polypeptide

Arginine/lysine polypeptide is a lab-synthesized multi-peptide that can help to preserve the natural collagen and elastin present in the skin by neutralizing substances that cause their degradation over time. It contains skin-friendly amino acids, namely l-arginine and l-lysine. These amino acids are classified as oligopeptides, which are smaller peptide chains consisting of at least two but not more than 20 amino acids. Peptides containing arginine are considered carrier peptides, which can improve the delivery of topical ingredients, while lysine-based peptides are known for their signaling properties.

Since both arginine and lysine are naturally present in the skin, arginine/lysine polypeptide is considered safe and non-irritating. Overall, this multi-peptide can potentially provide beneficial effects to the skin by preserving its natural components and enhancing the delivery of other topical ingredients.

Argireline

Argireline, also known as acetyl hexapeptide-8 or acetyl hexapeptide-3, is considered a neurotransmitter-inhibiting peptide, which may make it effective in reducing expression wrinkles. However, it is important to note that argireline cannot completely replace in-office wrinkle-smoothing injectable procedures. Some cosmetics claims regarding argireline’s benefits for reducing wrinkles may be overstated.

Studies have shown that a moisturizer containing a 10% concentration of argireline does not penetrate beyond the uppermost layers of skin, even after several hours of topical use. This means that it cannot address the underlying factors that contribute to the formation of expression lines. However, research has shown that argireline can penetrate deeper into the skin if certain formulary steps are followed, such as using an emulsion with a higher water content. This highlights the importance of selecting well-formulated skincare products that are optimized to deliver active ingredients effectively to the skin.

Azelaoyl Bis-Dipeptide-10

Azelaoyl Bis-Dipeptide-10 is a synthetic peptide that provides brightening, antioxidant, and protective benefits against advanced glycation end-products (AGEs) which can damage the skin’s support and lead to a loss of firmness.

Chemically, the Azelaoyl Bis-Dipeptide-10 molecule consists of an azelaic acid molecule with two amino acids (histidine and alanine) attached to both sides. The manufacturer suggests that the molecule functions by inhibiting two significant aging processes, glycation and oxidation.

Bacillus Ferment

Bacillus ferment is a probiotic peptide that has been found to have soothing and hydrating properties, which can help to strengthen the skin’s microbiome. This “invisible barrier” can reduce water loss and better maintain surface hydration.

Bacillus ferment is produced by fermenting Bacillus subtilis bacteria with various strains of yeast or other compounds. This process can create different types of ferments with unique properties. Some types of ferments have enzymatic activity that can break down keratin proteins found on the skin’s surface, while others support the skin’s microbiome.

Higher amounts of this ferment may be beneficial for improving the appearance of blemish-prone skin. This is mostly due to its soothing action and the positive impact it can have on the skin’s microbiome. Bacillus ferment can help to support the natural balance of microorganisms on the skin, which can contribute to a healthier and more radiant complexion.

Copper Tripeptide-1

Copper Tripeptide-1 (GHK-Cu) is a copper-peptide complex that has wound healing and anti-inflammatory properties and can stimulate the breakdown of unhealthy collagen in scar tissue while promoting the production of good collagen.

GHK-Cu is a complex of copper and peptides that occurs naturally in bodily fluids such as plasma, saliva, and urine.

It can also improve the production of other skin-identical ingredients, has antioxidant effects, and shows promise in improving skin elasticity, firmness, and reducing wrinkles. In addition, it can enlarge hair follicles and promote hair growth, although it may also cause slight facial hair growth.

Decarboxy Carnosine HCL

Decarboxy carnosine HCL, also known as carcinine, is commonly used in skincare as an antioxidant to protect against environmental stressors. It is a synthetic peptide designed to mimic a natural peptide found in the body. It

While there is not enough published research to confirm its collagen-boosting benefits, there is evidence to suggest that it may have antiglycation effects, which can help maintain skin’s collagen and elastin. Since it is a derivative of carnosine, it is believed to offer similar anti-aging benefits as this naturally occurring peptide in the body.

Dipalmitoyl Hydroxyproline

Dipalmitoyl hydroxyproline is a form of hydroxyproline, which signals the skin to repair its supportive structures, resulting in fewer visible lines and wrinkles. Dipalmitoyl hydroxyproline is a form of hydroxyproline that can dissolve in oil. Hydroxyproline is the main amino acid present in collagen.

To increase its effectiveness, it is recommended to pair dipalmitoyl hydroxyproline with oils or glycols. In addition to supporting collagen in the skin, it also helps to counteract matrix metalloproteinases, which are enzymes that can break down collagen. When these enzymes are not kept in check, it can lead to skin sagging and thinning lips.

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Dipeptide diaminobutyroyl benzylamide diacetate, also known as SYN®-AKE, is a small tripeptide molecule that is said to mimic the activity of snake venom toxin Waglerin 1, paralyzing muscle contraction related to wrinkles. It is marketed as a neurotransmitter-inhibiting peptide that can target expression lines, similar to injectable procedures.

Glycoproteins

Glycoproteins are a type of protein that are linked to a sugar molecule, as the prefix “glyco” means “sugar”. These proteins are naturally present throughout the body, including on the surface of the skin. In the skin, glycoproteins work alongside other important ingredients such as glycerin, ceramides, and hyaluronic acid to maintain the skin’s health and appearance. By reinforcing the skin’s barrier strength, glycoproteins can help to keep the skin smooth and intact.

Glycoproteins are also valuable in skincare products because they can help to enhance the solubility and stability of other important peptides. By adding glycoproteins to a skincare formula alongside specific peptides, manufacturers can improve the delivery of these active ingredients to the skin, resulting in better results.

Hexanoyl Dipeptide-3 Norleucine Acetate

Hexanoyl Dipeptide-3 Norleucine Acetate is a synthetic tripeptide that promotes the proper shedding of the skin’s surface, resulting in more vibrant and smoother skin, and visibly reduced wrinkles. It competes with damaged proteins on the skin’s surface that can obstruct exfoliation and enhances the skin’s shedding ability. This peptide can be combined with exfoliating acids.

Hexanoyl Dipeptide-3 Norleucine Acetate, which has the trade name of PerfectionPeptide P3, is a new tripeptide that has multiple benefits for the skin. It can reactivate the natural desquamation process of the skin, resulting in better skin quality with fewer imperfections and signs of aging. It also speeds up cell renewal, hydrates the skin, refines its texture, and reduces wrinkle depth.

Matrixyl 3000

Matrixyl™ 3000 is a trademarked combination of two synthetic peptides: palmitoyl tripeptide-1 (formerly known as palmitoyl oligopeptide) and palmitoyl tetrapeptide-7. These peptides act as messengers to send repair signals through the skin’s surface, which can help reduce visible skin damage, strengthen the skin’s supportive elements, and soothe signs of skin sensitization. Studies have shown that consistent use of Matrixyl™ 3000 can lead to a reduction in the depth of wrinkles.

While the suggested usage concentration of Matrixyl™ 3000 is 3%, the actual peptide concentration in the blend is much lower, as peptides can be effective in very small amounts. The safety and toxicity of both peptides in Matrixyl™ 3000 have been reviewed by independent experts and deemed safe by the Cosmetic Ingredient Review Expert Panel.

Myristoyl Hexapeptide-16

Myristoyl Hexapeptide-16 is a synthetic peptide that is linked to a fatty acid and is known to have several benefits for the skin. By combining myristic acid with hexapeptide-16, it can help improve the skin’s resilience, visibly calm and smoothen the skin. This peptide is categorized as a protein-stimulating peptide, which means it can help the surface of the skin to become more resistant to moisture loss and look better.

Myristoyl Hexapeptide-16 is capable of stimulating keratin genes, which convinces the cells to produce more keratin. This structural protein is super important for hair, nails, and the outermost layer of the skin.

Myristoyl Hexapeptide-16 is often found combined with Myristoyl Pentapeptide-17 in eyelash growth products. These two peptides together can visibly increase eyelash length after two weeks. By using Myristoyl Hexapeptide-16 and Myristoyl Pentapeptide-17, the two peptides can stimulate keratin genes in eyelash hair follicles, resulting in longer, fuller lashes.

Myristoyl Hexapeptide-17

Myristoyl pentapeptide-17 is commonly used in skincare products due to its ability to improve the moisture content of the skin and enhance its elasticity and overall resilience. This peptide is a laboratory-made protein fragment consisting of five amino acids.

This peptide works by stimulating the production of collagen, a protein that gives the skin its structure and helps it to maintain its firmness and elasticity. By promoting collagen synthesis, myristoyl pentapeptide-17 can help to reduce the appearance of fine lines and wrinkles, giving the skin a more youthful and radiant appearance.

Additionally, myristoyl pentapeptide-17 has been shown to have antioxidant properties, which can help to protect the skin from damage caused by environmental stressors such as pollution and UV radiation. By neutralizing harmful free radicals, this peptide can help to prevent premature aging and support the skin’s natural repair processes.

Myristoyl Hexapeptide-31

Myristoyl Tripeptide-31 has been shown to have a retinol-like effect on the skin’s appearance, which can help to improve its texture, tone, and visible firmness. Its use in skincare products has become increasingly popular due to its potential anti-aging benefits and ability to promote a more youthful-looking complexion.

This synthetic peptide is created by combining myristic acid, a type of fatty acid, with tripeptide-31, a chain of three amino acids.

Oligopeptide-10

Oligopeptide-10 shows promise effective in managing bacteria that cause acne. It can work alone or in combination with the well-known acne-fighting exfoliant, salicylic acid. Oligopeptide-10, also referred to as granactive oligopeptide-10, is a man-made bio-active peptide comprising of 15 amino acids.

Further research has demonstrated that oligopeptide-10 can be beneficial for individuals with sensitive skin. It can help to target and improve the factors that contribute to visible redness.

Palmitoyl Dipeptide-10

Palmitoyl dipeptide-10 has antioxidant and anti-aging properties and is a natural protein present in the body, which can enhance skin firmness. This is a synthetic peptide composed of palmitic acid and dipeptide-10, which consists of the amino acids alanine and histidine.

Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine

Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine is a synthetic signal peptide that has several benefits for the skin. It is specifically designed to support the collagens and proteins present in the dermal-epidermal junction, which helps to improve skin texture and make it feel firmer.

The ingredient is created by combining palmitic acid, an amino acid called lysine, valine, and threonine, and a complex amino acid called diaminobutyric acid. This results in a complex ingredient that is capable of delivering visible results when used in amounts between 1-3%, which is based on clinical data.

Research has shown that the use of Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine in combination with other peptides is particularly effective. When combined with other supporting peptides, it can provide a synergistic effect that leads to impressive results.

Palmitoyl Hexapeptide-12

Palmitoyl hexapeptide-12, also known as pal-KTTKS, is a lab-made peptide that blends palmitic acid and amino acids to enhance its penetration and stability in the skin. This peptide mimics naturally occurring peptides in the skin, making it easily recognized and utilized. Its main function is to improve skin firmness, minimize wrinkles, and strengthen the skin’s barrier by improving moisture retention.

Palmitoyl Oligopeptide

Palmitoyl oligopeptide, also known as pal-KTTKS, is a synthetic blend of fatty acid and amino acids that has skin-restoring abilities. It can promote the growth of collagen, elastin, and hyaluronic acid, which improves the skin’s water content and increases dermis thickness while reducing microgrooves. Its primary effect is to enhance skin elasticity and thickness.

As more peptides were synthesized for skincare, specific names were developed to avoid confusion, and palmitoyl oligopeptide was formerly used as a catchall term for several peptides, including palmitoyl hexapeptide-12.

Palmitoyl Pentapeptide-4

Palmitoyl Pentapeptide-4, also known as Matrixyl, is a peptide used particularly for its anti-wrinkle properties and to enhance overall skin texture. The peptide is typically attached to palmitic acid for better skin penetration and solubility.

Clinical studies have been promising, with significant improvements seen even at low concentrations of just 3 parts per million. In comparison to retinol, a well-established anti-aging ingredient, Palmitoyl Pentapeptide-4 has shown similar wrinkle-reducing abilities while being better tolerated by the skin. While most research on this peptide is sponsored by the manufacturer, it is a widely used and recognized ingredient in the skin care industry.

Palmitoyl Pentapeptide-7

Palmitoyl tetrapeptide-7 is a synthetic peptide commonly used in skin care products for its skin-restoring and soothing properties. The peptide helps to reduce factors that cause skin irritation and loss of firmness, allowing the skin to repair itself and reduce the appearance of wrinkles. This peptide consists of four amino acids, including glutamine, glycine, arginine, and proline, along with palmitic acid.

It is typically used at very low percentages in formulations, but may be blended with other peptides for more targeted results. It works by reducing the production of interleukin-6, a signal molecule that promotes skin inflammation and degradation of important components like collagen. Palmitoyl tetrapeptide-7 is often used in combination with Palmitoyl Tripeptide-1 in the Matrixyl 3000 complex.

Palmitoyl Tetrapeptide-72 Amide

Palmitoyl tetrapeptide-72 amide has been clinically shown to improve surface firmness and tensile strength by promoting the maintenance of youthful shape and resistance to age-related deterioration. This peptide is a synthetic signal peptide consisting of alanine, arginine, histidine, and tyrosine, combined with palmitoyl chloride. It is safe for sensitive skin and typically used in concentrations of 1-2%.

Palmitoyl tetrapeptide-72 amide, also know as Skinarch™, is a novel peptide that supports the trend of inclusive beauty and promotes the formation of well-organized collagen fibrils for proper biotensegrity in the skin. It works on all four collagen families and has been shown to be effective in both light-pigmented and dark-pigmented skin.

Palmitoyl Tetrapeptide-1

Palmitoyl tripeptide-1, also known as pal-GHK and palmitoyl oligopeptide, is a synthetic peptide that can improve the appearance of skin damage and strengthen its underlying supportive structures. As a messenger peptide, it instructs the skin to look better by reducing signs of sun damage such as wrinkles and rough texture. Research suggests that it has similar anti-aging benefits to retinol, and it is often used in combination with it for even greater benefits.

Palmitoyl tripeptide-1 is a small peptide consisting of three amino acids, with the GHK component being a type I collagen fragment. By mimicking the breakdown of collagen in the skin, it signals the skin to produce more collagen, resulting in fewer wrinkles and more youthful-looking skin. Palmitoyl tripeptide-1 is commonly used in Matrixyl 3000, which also contains Palmitoyl Tetrapeptide-7, to work in synergy for wrinkle reduction and younger-looking skin.

Palmitoyl Tetrapeptide-5

Palmitoyl Tripeptide-5 is a synthetic peptide that is believed to have a positive effect on skin firmness. It consists of three amino acid chains linked together with fatty acids and can penetrate deep into the dermis to stimulate collagen and elastin production.

By interacting with specific skin receptors, Palmitoyl Tripeptide-5 can reduce the appearance of wrinkles and fine lines, make the skin look healthier and fresh, and increase the firmness of the skin. It also works in conjunction with hyaluronic acid and elastin to increase water content and help remove toxins, while supporting healthy skin cell functioning.

Palmitoyl Tetrapeptide-8

Pentapeptide-18

Pentapeptide-18 is a neuropeptide that can reduce signs of aging, including wrinkles and expression lines, by mimicking the natural mechanism of enkephalins. It is effective in reducing the depth of wrinkles caused by muscle contractions, and has been found to promote anti-aging benefits, such as improving the appearance of facial lines around the eyes, forehead, and mouth.

Pentapeptide-18 works in synergy with acetyl hexapeptide-8 (Argireline) to hinder muscle contraction in two different stages, resulting in botulinum-like effects. This solution is trade named as Argirelox.

Adding D-tyrosine to the pentapeptide-18 configuration may help to fade dark spots and uneven skin tone. However, more independent studies are necessary to validate these findings.

Pentapeptide-59

Pentapeptide-59 is a synthetic ingredient that mimics a sea anemone protein, which has been found to calm sensitive skin and reduce irritation. It contains arginine, histidine, phenylalanine, and valine, and when applied to the skin, it has been shown to reduce redness and neutralize signals in the upper layers of the skin that can cause sensitivity.

To keep the peptide stable during use, it is typically paired with emollient fatty acids like shea butter or lecithin. This makes it an ideal ingredient for sensitive skin care, neurocosmetics, and comforting formulations that aim to minimize the skin’s response to stress and reduce the itching sensation associated with sensitive skin.

Saccharomyces/Calcium Ferment

Saccharomyces/Calcium Ferment is an extract of yeast that is fermented in the presence of calcium ions. While it has no known direct benefits for the skin, it is believed that it could help improve hydration.

The calcium in the epidermis plays a crucial role in regulating the growth and shedding of skin cells. Insufficient calcium can result in thin, dry, and fragile-looking skin, which is caused by a lack of calcium to promote new skin growth or to remove dead skin cells. Therefore, Saccharomyces/Calcium Ferment can aid in skin regeneration and protection.

Saccharomyces/Iron Ferment

Saccharomyces Iron Ferment is a natural ingredient derived from yeast cells that are rich in essential minerals, vitamins, and amino acids. It is known for its ability to increase the level of iron in the skin, which can help to improve skin texture and reduce the appearance of fine lines and wrinkles.

Saccharomyces Iron Ferment is also believed to have antioxidant properties that can protect the skin from free radical damage, helping to maintain a youthful and radiant complexion. This ingredient is often used in formulations designed to nourish and revitalize the skin, and it is suitable for all skin types.

Sh-Polypeptide-121

Sh-Polypeptide-121 is a signal peptide produced through bacterial fermentation that is bio-identical and vegan. Studies suggest improvement to the skin’s tensile strength by supporting its underlying elements and can reduce the appearance of wrinkles. It works well in conjunction with vitamin C, resulting in a significant improvement in the skin’s firmness and texture, and it can also soothe puffiness and redness in the skin.

Sh-Polypeptide-121 is the first biomimetic vegan collagen for skincare and is virtually colorless and odorless, making it highly compatible and pure. Compared to marine collagen, Sh-Polypeptide-121 has been shown to have superior collagen, elastin, and fibronectin-boosting effects.

Silk Protein

Silk protein, also known as sericin, is a substance derived from silk and has water-binding properties for the skin. It doesn’t matter if the protein is from animals or plants, as the skin can’t tell the difference. Some research suggests that silk protein may have antioxidant properties when applied topically.

Silk protein is made up of fibroin and sericin, with fibroin being rich in glycine, alanine, and serine, which form a sheet structure that provides the comfortable touch of silk. Sericin contains amino acids with hydroxy groups that offer excellent moisturizing effects.

SYN-TC®

SYN-TC® is a synthetic blend of three peptides that supports collagen quality and maintenance in the skin’s underlying layers, resulting in firmer, plumper, and more elastic skin. The complex of peptides work together, and one of the key peptides, palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine, has a synergistic effect with supporting peptides, boosting its ability to support specific collagens and proteins in the skin’s dermal-epidermal junction.

SYN®-TC is designed for high-performing, anti-aging facial formulas and significantly increases the formation of various collagens to make skin smoother with a softer touch and a more youthful appearance. A consumer study confirmed the effectiveness of the product, showing smoother skin in just 28 days with twice daily use at a concentration of 2.5%.

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Tetradecyl aminobutyroylvalylaminobutyric urea trifluoroacetate is a synthetic tripeptide that is claimed to improve skin’s ability to maintain hydration and restore firmness. Clinical studies have shown that it can improve the “biomechanical properties” of skin, helping it to bounce back and appear smoother. It is also said to boost the synthesis of hyaluronic acid, an important component for skin hydration and plumpness, and improve collagen fiber quality.

This peptide is suggested for use in firming and remodeling treatments and is marketed as a “needle-free hyaluronan booster”.

Tetrapeptide-30

Tetrapeptide-30 is a synthetic peptide made up of the amino acids proline, glutamic acid, and lysine. It has been found to have a positive effect on the skin, interrupting pathways that lead to skin discoloration and promoting a brighter, more even skin tone. It has also been shown to have anti-inflammatory properties, making it an excellent choice for a wide range of skin care products.

Clinical studies have demonstrated that Tetrapeptide-30 can help reduce hyperpigmentation, age spots, and redness in the skin. It has been found to be particularly effective in reducing melasma on ethnic skin, making it an excellent choice for ethnic skin care products. Additionally, it can help reduce acne lesions and promote a more youthful, radiant appearance.

Tetrapeptide-30 is commonly used in skin lightening and anti-aging products to help reduce the appearance of age spots and other pigmentation disorders. It is often combined with other active ingredients, such as vitamin-C derivatives, to enhance its effectiveness. With its soothing and revitalizing properties, Tetrapeptide-30 is a valuable ingredient in a wide range of skin care products designed to promote a more youthful, even skin tone.

Tridecapeptide-1

Tridecapeptide-1 is a synthetic peptide that consists of a specific combination of amino acids, namely alanine, leucine, lysine, and valine. Developed to target the appearance of wrinkles and expression lines on the skin, this peptide interacts with acetylcholine receptors in the upper layers of the skin, which helps to smooth out the lines.

Tridecapeptide-1 has been clinically proven to be effective on human skin, with visible results being observed within 15 minutes of application. Continued use of the peptide leads to a reduction in visible wrinkles, especially around the eyes and mouth. Additionally, it helps to improve the texture of rough skin.

Tripeptide-1

Tripeptide-1, also known as GHK, is a synthetic signal peptide composed of glycine, histidine, and lysine. When working with copper, it can help repair substances that have deteriorated due to aging and sun exposure. Tripeptide-1 is believed to stimulate collagen production in the skin, resulting in smoother and firmer skin with fewer wrinkles.

As a carrier peptide, Tripeptide-1 can help stabilize and deliver copper in the skin, forming a complex called GHK-Cu. GHK-Cu is a well-researched peptide with a variety of benefits for the skin. Tripeptide-1 is found in Matrixyl 3000, where it is attached to palmitic acid to increase skin penetration. When used on its own, Tripeptide-1, under the trade name Kollaren, can also stimulate the production of other essential skin proteins such as fibronectin, elastin, and laminin. It may even help acne-prone skin by boosting tissue repair and speeding up the healing process of acne scars.

Tripeptide-29

Tripeptide-29 is a synthetic peptide composed of amino acids glycine, proline, and hydroxyproline derivative. It has been shown to enhance the skin’s supportive elements, resulting in improved skin texture, reduced fine lines, and a hydrated appearance. Due to its small size, it can easily penetrate the skin’s upper layers, making it an effective ingredient in skincare products. It is typically used at a concentration of 0.1-1%.

The unique feature of Tripeptide-29 is its exceptional purity, which is obtained through modern peptide synthesis from non-animal and non-GMO sources.

Tripeptide-32

Tripeptide-32 is a synthetic peptide consisting of the amino acids proline, serine, and threonine. While it is known to have skin-restoring abilities and can help retain moisture in the skin, other claims regarding its benefits are unproven. However, recent research suggests that this hydrophilic peptide can activate skin genes such as CLOCK and PER1, which regulate the skin’s biological clock. This allows damaged skin cells to be repaired both during the day and at night, which can prevent signs of aging.

You can find Tripeptide-32 in cosmetic products like lotions, morning and night creams, and eye essences, as it can help moisturize the skin, reduce wrinkles, and slow down the aging process.